Sequenda Lashawn "Shawn" Tucker, 33, of Anniston was arrested and charged with second-degree domestic violence, a felony.
Tucker and her 40-year-old boyfriend allegedly got into an argument at a home on the 2800 block of Old Wilmer Avenue in the early morning.
She took a kitchen steak knife and stabbed him, police said, striking an artery.
Her boyfriend ran to a neighbor's house, bleeding profusely, investigators said.
The neighbor drove the victim to Stringfellow Memorial Hospital, where he underwent immediate surgery, police said.
Her bond is $5,000 and she is to appear in court Oct. 16.